Urticaria pigmentosa
Urticaria pigmentosa shi ne mafi yawan nau'in mastocytosis na fata. Cuta ce da ba kasafai ba ke haifar da yawan ƙwayoyin mast a cikin fata, waɗanda ke haifar da amya ko raunuka a kan fata idan an taɓa su. Ana yawan ganin tabo ja ko launin ruwan kasa a fata, yawanci a kusa da kirji, goshi, da baya. Wadannan ƙwayoyin mast, idan sun fusata (misali ta hanyar shafa fata ko zafi mai ƙarfi), suna sakin histamine mai yawa, wanda ke haifar da alamomin rashin lafiyar da ke haifar da amya a wurin da aka taɓa, wani lokaci ana kiransa “alamar Darier”.
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ReferencesMastocytosis wani yanayi ne da ke haifar da yawaitar mast cells, sau da yawa ana samun su a sassa daban‑daban na jiki kamar fata, bargon kashi, da tsarin narkewar abinci. A cewar Hukumar Lafiya ta Duniya (WHO), cutaneous mastocytosis za a iya rarraba zuwa manyan iri uku. Nau'in farko (mastocytomas) ya ƙunshi raunuka kaɗai ko kaɗan (≤3). Nau'i na biyu (urticaria pigmentosa) ya ƙunshi raunuka da yawa, yawanci daga sama da 10 zuwa ƙasa da 100. Nau'in na ƙarshe yana nuna alamar a fata. Urticaria pigmentosa shine mafi yawan nau'in cutaneous mastocytosis a cikin yara, amma kuma yana iya faruwa a cikin manya. Yawanci yanayin rashin lahani ne wanda sau da yawa yakan inganta yayin samartaka. Ba kamar manyan mastocytosis ba, urticaria pigmentosa ba ya shafar gabobin ciki. Ɗayan siffa ta musamman ta urticaria pigmentosa shine halin sa na haifar da ƙanƙanta, ƙaiƙayi, ja‑ja‑ja, ko tabo mai launin rawaya‑kasa ko raunuka a kan fata, wanda aka fi sani da amya. Waɗannan tabo yawanci suna bayyana a lokacin ƙuruciya kuma suna iya wucewa tsawon rayuwa.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Wata yarinya ‘yar shekara 6 ta shigo da wasu diloli masu duhu waɗanda suka fara bayyana a fatar kan ta, sannan suka bazu a fuskarta da jikinta tsawon watanni shida da suka gabata. Ta ambata jin su tashi, su yi ja, da ƙaiƙayi lokacin da aka matsi. Ba ta fuskanci firgita, amai, gudawa, ko hushi ba, kuma tarihin likitanta na sirri da na dangi bai ba da alamun da suka dace ba. Bayan an duba, mun ga ɗimbin duhu a fatar kai, goshinta, fuska, da wuyanta, tare da ɗan ɗaga duhu a ƙirjinta da bayanta. Shafa wuraren a hankali ya sa su kumbura da ƙaiƙayi a cikin mintuna 2, amma alamun sun ɓace cikin mintuna 15‑20 (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
